
{"id":217243,"date":"2020-04-11T14:28:03","date_gmt":"2020-04-11T18:28:03","guid":{"rendered":"https:\/\/oncubanews.com\/en\/?p=217243"},"modified":"2020-04-11T14:28:03","modified_gmt":"2020-04-11T18:28:03","slug":"cuba-working-on-coronavirus-vaccine","status":"publish","type":"post","link":"https:\/\/oncubanews.com\/en\/cuba\/cuba-working-on-coronavirus-vaccine\/","title":{"rendered":"Cuba working on coronavirus vaccine"},"content":{"rendered":"<p>Dr. Rolando P\u00e9rez Rodr\u00edguez, director of Science and Innovation of BioCubaFarma, spoke at the <em>Mesa Redonda<\/em> television program this Friday about the role of the biopharmaceutical industry in the field of science and innovation against the coronavirus.<\/p>\n<p>He said that the laboratories of the Center for Genetic Engineering and Biotechnology <a href=\"https:\/\/www.paho.org\/cub\/index.php?option=com_content&amp;view=article&amp;id=222:centro-ingenieria-genetica-biotecnologia-cigb&amp;Itemid=528\" target=\"_blank\" rel=\"noopener noreferrer\">(CIGB)<\/a> were working on a vaccine to induce specific protective immunity. \u201cThis is a future project that will allow, in a long-term control of the disease, if there is a re-emergence, having a specific vaccine.\u201d<\/p>\n<p>He said that there is also a vaccine candidate produced by the Carlos J. Finlay Institute based on components of the Cuban vaccine against meningitis, which activates the innate immune system and gives some capacity to react against the virus.<\/p>\n<p>He assured that today there are 41 vaccine projects around the world, but that none has shown effective use, and only five have started the first studies in patients. \u201cCuban scientists are in that same race,\u201d he said.<\/p>\n<p>He also spoke about the development of technologies that have allowed access to a set of products for different pathologies, some registered and others under investigation.<\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"5vH4eLmcLF\"><p><a href=\"https:\/\/oncubanews.com\/cuba\/cientificos-cubanos-trabajan-en-una-vacuna-contra-el-coronavirus\/\">Cient\u00edficos cubanos trabajan en una vacuna contra el coronavirus<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"\u00abCient\u00edficos cubanos trabajan en una vacuna contra el coronavirus\u00bb \u2014 OnCubaNews\" src=\"https:\/\/oncubanews.com\/cuba\/cientificos-cubanos-trabajan-en-una-vacuna-contra-el-coronavirus\/embed\/#?secret=bJzTv5wtwh#?secret=5vH4eLmcLF\" data-secret=\"5vH4eLmcLF\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>Of those projects, he said, nine are in clinical studies or intervention trials in at-risk patients and vulnerable groups. Another six are in the research and development phase in the laboratories of the group\u2019s companies.<\/p>\n<p>He explained that innate immunity, the first line of defense against infection, plays a critical role in the course of COVID-19. But there are patients in whom the virus escapes that action. When this occurs, he said, high viral particles titers are recorded, triggering lung disease.<\/p>\n<p>In patients suffering from other diseases\u2015the so-called co-morbidity\u2015a hyper-inflammatory reaction is generated that leads to death. \u201cThe patient does not die of infection, he dies of an autoimmune reaction,\u201d he said.<\/p>\n<p>He noted that the logic of intervening in the course of the disease is, first, to stimulate immunity in high-risk persons to achieve a mild course of the disease, and, second, to reduce the viral load in the initial stages.<\/p>\n<p>And also to reduce the hyper-inflammatory reaction in patients who develop it. In this way, the rate of serious and critical cases must be lowered, as well as the number of deaths.<\/p>\n<p>\u201cFor the initial treatment of the disease,\u201d he said, \u201cCuban interferon, which has antiviral and immunopotentiating activity,\u201d produced by the CIGB, is being used.<\/p>\n<p>For the management of inflammatory reactions, he noted, two products were being assessed: a monoclonal antibody from the Center for Molecular Immunology and a peptide from the Center for Genetic Engineering and Biotechnology that stimulates cells that regulate the immune response.<\/p>\n<p>Lastly, he said that five biotech products were being considered for prophylactic use in risk and vulnerable groups, capable of stimulating the immune system.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Rolando P\u00e9rez Rodr\u00edguez, director of Science and Innovation of BioCubaFarma, spoke at the Mesa Redonda television program this Friday about the role of the biopharmaceutical industry in the field of science and innovation against the coronavirus. He said that the laboratories of the Center for Genetic Engineering and Biotechnology (CIGB) were working on a [&hellip;]<\/p>\n","protected":false},"author":3134,"featured_media":217244,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13902],"tags":[29532,15273],"ppma_author":[33546,8689],"class_list":["post-217243","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cuba","tag-coronavirus-in-cuba","tag-cuban-science"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cuba working on coronavirus vaccine | OnCubaNews English<\/title>\n<meta name=\"description\" content=\"Reiterated the director of Science and Innovation of BioCubaFarma, Dr. Rolando P\u00e9rez Rodr\u00edguez, at the Mesa Redonda television program, and explained the development 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