{"id":232437,"date":"2020-12-30T11:32:24","date_gmt":"2020-12-30T16:32:24","guid":{"rendered":"https:\/\/oncubanews.com\/en\/?p=232437"},"modified":"2020-12-30T11:32:24","modified_gmt":"2020-12-30T16:32:24","slug":"cuba-negotiates-with-other-countries-to-develop-phase-3-of-soberana-02-vaccine","status":"publish","type":"post","link":"https:\/\/oncubanews.com\/en\/cuba\/cuba-negotiates-with-other-countries-to-develop-phase-3-of-soberana-02-vaccine\/","title":{"rendered":"Cuba negotiates with other countries to develop phase 3 of Soberana 02 vaccine"},"content":{"rendered":"<p>Cuba is negotiating to develop in other countries the last phase of trials of one of its four vaccine projects against SARS-CoV-2, since the \u201clow prevalence\u201d of the virus on the island prevents these tests from being carried out effectively.<\/p>\n<p>\u201cNegotiations are progressing to develop Phase 3 of the Soberana 02 clinical trial in other countries, due to the low prevalence of COVID-19 in the Cuban population,\u201d indicates a <a href=\"https:\/\/www.presidencia.gob.cu\/es\/noticias\/las-vacunas-soberanas-avanzan-de-manera-importante\/\" target=\"_blank\" rel=\"noopener\">note<\/a> from the Presidency released this Tuesday in state media.<\/p>\n<p>The candidate referred to in the negotiations is Soberana 02, developed by the Finlay Vaccine Institute (IFV) and which has just entered phase 2 of clinical trials. This stage will involve nearly a thousand volunteers as of January, who will be administered the preparation in \u201cdifferent formulations,\u201d said the director general of the IFV, Vicente V\u00e9rez, quoted in the note.<\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"omhXANaAGD\"><p><a href=\"https:\/\/oncubanews.com\/en\/cuba\/second-phase-of-cuban-soberana-02-vaccine-candidates-clinical-trials-approved\/\">Second phase of Cuban Soberana 02 vaccine candidate\u2019s clinical trials approved<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Second phase of Cuban Soberana 02 vaccine candidate\u2019s clinical trials approved&#8221; &#8212; OnCubaNews English\" src=\"https:\/\/oncubanews.com\/en\/cuba\/second-phase-of-cuban-soberana-02-vaccine-candidates-clinical-trials-approved\/embed\/#?secret=lQijchiGLk#?secret=omhXANaAGD\" data-secret=\"omhXANaAGD\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>This figure varies with respect to those released in previous days, when V\u00e9rez declared to the state newspaper Granma that phase 2 would involve about a hundred people, which would increase to between 300 and 600 in phase II-B.<\/p>\n<p>According to the scientist, said candidate \u201chas shown an early immune response (at 14 days), which makes it possible to go on to phase 2 of the clinical trial more quickly.\u201d<\/p>\n<p>Once this second phase is concluded and evaluated, phase 3 will begin, in which some 150,000 people will participate in Havana\u2015the Cuban province with the highest rates of contagion in recent weeks\u2015and a number yet to be determined if the negotiations are finally finalized, to test it in other countries as well.<\/p>\n<p>Sovereign 02 combines the virus antigen and tetanus toxoid, and also uses aluminum hydroxide to stimulate the immune system response.<\/p>\n<p>V\u00e9rez \u201cratified the country\u2019s ability to immunize the Cuban population against the SARS-CoV-2 virus in the first half of 2021,\u201d adds the note, released on the occasion of a visit to the Finlay Institute on Monday by Cuban President Miguel D\u00edaz-Canel.<\/p>\n<figure id=\"attachment_232440\" aria-describedby=\"caption-attachment-232440\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-232440\" src=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1.jpg\" alt=\"\" width=\"1200\" height=\"843\" srcset=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1.jpg 1200w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1-300x211.jpg 300w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1-1024x719.jpg 1024w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1-768x540.jpg 768w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1-750x527.jpg 750w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2020\/12\/1a0389c6b8718e7731c8bcf8d1aed1e766380feb-1-1140x801.jpg 1140w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><figcaption id=\"caption-attachment-232440\" class=\"wp-caption-text\">Several people in protective suits against the coronavirus check the work material inside the red zone at the Jardines del Rey international airport in Cayo Coco in Cuba. EFE\/Ernesto Mastrascusa\/Archive.<\/figcaption><\/figure>\n<p>The president, who was informed about the progress of Soberana 01 and Soberana 02, praised the work of the group of researchers, mostly women, and highlighted that except for Cuba \u201cno third world country has a COVID-19 vaccine in the clinical trial,\u201d says the official statement.<\/p>\n<p>The IFV is also developing the candidate Soberana 01, which is about to conclude phase 1 of clinical trials and, according to the director of the center, \u201chas also shown safety and a very good immune response, but it is slower due to the time it takes between one dose and another.\u201d<\/p>\n<p>In addition to these two projects of the Finlay Institute, the Center for Genetic Engineering and Biotechnology (CIGB) of the Caribbean country is working on two other candidates: Abdala (intramuscular) and Mambisa (intranasal), which will begin clinical trials in which each will be tested in two phases.<\/p>\n<p>Cuba, which to date has a total of 11,601 cases of coronavirus and 143 deaths, has a recognized biotechnology and pharmaceutical industry that currently produces eight vaccines against diseases such as meningitis, lung cancer (therapeutic) and solid tumors, among others.<\/p>\n<p>Most of the Caribbean country entered a \u201cnew normal\u201d stage in October that includes the operation of activities and services at full capacity, although some measures such as the mandatory use of a mask in public places and physical distancing are maintained.<\/p>\n<p>The authorities announced this week new measures to curb a rising wave of infections attributed to the reopening of international airports in mid-October, and a month later in the case of Havana.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cuba is negotiating to develop in other countries the last phase of trials of one of its four vaccine projects against SARS-CoV-2, since the \u201clow prevalence\u201d of the virus on the island prevents these tests from being carried out effectively. \u201cNegotiations are progressing to develop Phase 3 of the Soberana 02 clinical trial in other [&hellip;]<\/p>\n","protected":false},"author":3606,"featured_media":232438,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[33393,13902],"tags":[29532,33386],"ppma_author":[33548,17270],"class_list":["post-232437","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-coronavirus","category-cuba","tag-coronavirus-in-cuba","tag-cuban-vaccine-against-covid-19"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cuba negotiates with other countries to develop phase 3 of Soberana 02 vaccine | OnCubaNews English<\/title>\n<meta name=\"description\" content=\"Negotiations are progressing to develop Phase 3 of the 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