{"id":233337,"date":"2021-01-19T14:27:26","date_gmt":"2021-01-19T19:27:26","guid":{"rendered":"https:\/\/oncubanews.com\/en\/?p=233337"},"modified":"2021-01-19T14:27:26","modified_gmt":"2021-01-19T19:27:26","slug":"cuban-covid-19-nasal-vaccine-concludes-first-phase-of-trials","status":"publish","type":"post","link":"https:\/\/oncubanews.com\/en\/cuba\/cuban-covid-19-nasal-vaccine-concludes-first-phase-of-trials\/","title":{"rendered":"Cuban COVID-19 nasal vaccine concludes first phase of trials"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">The Cuban Mambisa <\/span><a href=\"https:\/\/oncubanews.com\/tag\/vacuna\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">COVID-19 vaccine candidate<\/span><\/a><span style=\"font-weight: 400;\"> concluded the period of clinical trials called \u201cshort cycle,\u201d stipulated for days zero, 14 and 28 of the schedule, <\/span><em><a href=\"https:\/\/www.prensa-latina.cu\/index.php?o=rn&amp;id=424302&amp;SEO=vacuna-nasal-anti-covid-19-de-cuba-cierra-ciclo-corto-de-ensayo\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Prensa Latina<\/span><\/a><\/em><span style=\"font-weight: 400;\"> reported.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The drug, developed by scientists from the Cuban Center for Genetic Engineering and Biotechnology (CIGB), began human trials on December 7 with 88 volunteers, explained the head of the trial, Miladys Limonta.<\/span><\/p>\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"es\" dir=\"ltr\"><a href=\"https:\/\/twitter.com\/hashtag\/Mambisa?src=hash&amp;ref_src=twsrc%5Etfw\">#Mambisa<\/a> y <a href=\"https:\/\/twitter.com\/hashtag\/Abdala?src=hash&amp;ref_src=twsrc%5Etfw\">#Abdala<\/a>, actualmente en Fase I de ensayos cl\u00ednicos, los cient\u00edficos cubanos se preparan para actuar ante variantes de la enfermedad con mayor capacidad de infecci\u00f3n y de agravar los da\u00f1os a la salud.<a href=\"https:\/\/t.co\/6zDC4XnpHw\">https:\/\/t.co\/6zDC4XnpHw<\/a> <a href=\"https:\/\/t.co\/mPdJMSrAAA\">pic.twitter.com\/mPdJMSrAAA<\/a><\/p>\n<p>&mdash; CIGBCuba (@CIGBCuba) <a href=\"https:\/\/twitter.com\/CIGBCuba\/status\/1350464994673111042?ref_src=twsrc%5Etfw\">January 16, 2021<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p><span style=\"font-weight: 400;\">The study participants received an intramuscular dose of the drug and another two intranasal doses, while another group received three administrations by the same route, indicates the source, citing the expert.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">After the first period of the trials, the safety of the vaccine candidate could be verified, as there were only mild adverse reactions, Limonta said.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once the evaluation of the results of the study by the Cuban regulatory entity has concluded, \u201cwe would move on to the long cycle, between days zero, 28 and 56,\u201d the scientist explained.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The other COVID-19 vaccine candidate developed by the CIGB also completed its short cycle that evaluates the dose ranges in a period of zero, 14 and 28 days, study leaders announced.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The clinical trials of the drug Abdala include 132 volunteers, who receive two doses of antigen or placebo intramuscularly.<\/span><\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"dkkZ6AVtSq\"><p><a href=\"https:\/\/oncubanews.com\/cuba\/cuba-inicia-segunda-fase-de-ensayos-clinicos-de-su-candidato-vacunal-soberana-02\/\">Cuba inicia segunda fase de ensayos cl\u00ednicos de su candidato vacunal Soberana 02<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"\u00abCuba inicia segunda fase de ensayos cl\u00ednicos de su candidato vacunal Soberana 02\u00bb \u2014 OnCubaNews\" src=\"https:\/\/oncubanews.com\/cuba\/cuba-inicia-segunda-fase-de-ensayos-clinicos-de-su-candidato-vacunal-soberana-02\/embed\/#?secret=uLfl8t0yeh#?secret=dkkZ6AVtSq\" data-secret=\"dkkZ6AVtSq\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">In the midst of the <\/span><a href=\"https:\/\/oncubanews.com\/cuba\/cuba-identifica-la-menor-cifra-de-casos-diarios-con-covid-19-en-los-ultimos-12-dias\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">worst outbreak of coronavirus infections<\/span><\/a><span style=\"font-weight: 400;\">, Cuba is pinning its hopes on four drugs to immunize the population.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to Mambisa and Abdala, the island has the vaccine candidates developed by the Finlay Institute: Soberana 01 and Soberana 02, the latter in phase II of clinical trials.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">On December 17, after preliminary positive results of phase I, Sovereign 02 received authorization from the Center for State Control of Medicines, Equipment and Medical Devices to advance to the next phase of clinical trials, therefore being the first Latin American drug to reach that stage.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Cuban Mambisa COVID-19 vaccine candidate concluded the period of clinical trials called \u201cshort cycle,\u201d stipulated for days zero, 14 and 28 of the schedule, Prensa Latina reported. The drug, developed by scientists from the Cuban Center for Genetic Engineering and Biotechnology (CIGB), began human trials on December 7 with 88 volunteers, explained the head [&hellip;]<\/p>\n","protected":false},"author":3134,"featured_media":233338,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13902],"tags":[29532,32668,15273],"ppma_author":[33546,8689],"class_list":["post-233337","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cuba","tag-coronavirus-in-cuba","tag-covid-19-vaccine","tag-cuban-science"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cuban COVID-19 nasal vaccine concludes first phase of trials | OnCubaNews English<\/title>\n<meta name=\"description\" content=\"The drug, developed by scientists from the Cuban 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