{"id":238408,"date":"2021-05-03T12:24:31","date_gmt":"2021-05-03T16:24:31","guid":{"rendered":"https:\/\/oncubanews.com\/en\/?p=238408"},"modified":"2021-05-03T12:24:31","modified_gmt":"2021-05-03T16:24:31","slug":"phase-iii-doses-application-of-abdala-candidate-clinical-trial-ends-in-eastern-cuba","status":"publish","type":"post","link":"https:\/\/oncubanews.com\/en\/coronavirus\/phase-iii-doses-application-of-abdala-candidate-clinical-trial-ends-in-eastern-cuba\/","title":{"rendered":"Phase III doses application of Abdala candidate clinical trial ends in eastern Cuba"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">The Abdala <\/span><a href=\"https:\/\/oncubanews.com\/en\/tag\/cuban-vaccine-against-covid-19\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">COVID-19 vaccine candidate<\/span><\/a><span style=\"font-weight: 400;\">, one of the five developed in Cuba that has already been tested in humans, concluded this Saturday the third and final phase of clinical trials, which began in March in the eastern part of the island.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The study applied in three-shot doses included more than 48,000 volunteers from the capitals of Santiago de Cuba, Guant\u00e1namo and Granma provinces, in order to test its effectiveness against <\/span><a href=\"https:\/\/oncubanews.com\/en\/coronavirus\/?amp\"><span style=\"font-weight: 400;\">COVID-19<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This was confirmed on Twitter by the BioCubaFarma conglomerate, which comprises the main entities of the pharmaceutical and biotechnology industry in the country, and the Center for Genetic Engineering and Biotechnology (CIGB), in charge of developing the vaccine candidate.<\/span><\/p>\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"es\" dir=\"ltr\">Concluy\u00f3 hoy <a href=\"https:\/\/twitter.com\/hashtag\/1demayo2021?src=hash&amp;ref_src=twsrc%5Etfw\">#1demayo2021<\/a>, la aplicaci\u00f3n de la tercera y ultimas dosis correspondientes a la Fase III del ensayo cl\u00ednico con el Candidato Vacunal <a href=\"https:\/\/twitter.com\/hashtag\/Abdala?src=hash&amp;ref_src=twsrc%5Etfw\">#Abdala<\/a>, que se desarrolla desde el 22 de marzo en las provincias de Granma, Santiago de Cuba y Guant\u00e1namo. <a href=\"https:\/\/t.co\/hmzNwQTDdy\">pic.twitter.com\/hmzNwQTDdy<\/a><\/p>\n<p>&mdash; BioCubaFarma (@BioCubaFarma) <a href=\"https:\/\/twitter.com\/BioCubaFarma\/status\/1388645000184049672?ref_src=twsrc%5Etfw\">May 2, 2021<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p><span style=\"font-weight: 400;\">In particular, the CIGB specified that the trial culminated with \u201cmore than 97% adherence to vaccination,\u201d among the 48,290 volunteers who received Abdala in the eastern region of Cuba.<\/span><\/p>\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"es\" dir=\"ltr\">Hoy <a href=\"https:\/\/twitter.com\/hashtag\/1ro?src=hash&amp;ref_src=twsrc%5Etfw\">#1ro<\/a> de Mayo CONCLUYE APLICACI\u00d3N DE \u00daLTIMA DOSIS DE ABDALA EN EL ENSAYO CL\u00cdNICO FASE III en las provincias de Granma, Santiago de Cuba y Guant\u00e1namo. <br \/>De los 48 290 voluntarios, a quienes se les aplic\u00f3 la dosis, culmina hoy con m\u00e1s de un 97% de adherencia a la vacunaci\u00f3n. <a href=\"https:\/\/t.co\/v88ZqBviuZ\">pic.twitter.com\/v88ZqBviuZ<\/a><\/p>\n<p>&mdash; CIGBCuba (@CIGBCuba) <a href=\"https:\/\/twitter.com\/CIGBCuba\/status\/1388692962914226179?ref_src=twsrc%5Etfw\">May 2, 2021<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p><span style=\"font-weight: 400;\">Researchers from the CIGB itself recently told state media that, once this stage is completed, the appearance of positive cases for the SARS-CoV-2 coronavirus among the study participants would begin to be evaluated. Dr. Verena Muzio, director of clinical research at the institution, explained that this will make it possible to compare the proportions between the vaccinated group and the one inoculated with a placebo, and thus evaluate the efficacy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The scientific center is also in charge of the Mambisa intranasal vaccine candidate, while Soberana 01, Soberana 02 and Soberana Plus are generated by the Finlay Vaccine Institute.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Abdala is also being applied at this time to health personnel and other risk groups in intervention studies carried out in Havana and in eastern Cuba. In addition, it will be part, together with Soberana 02, of <\/span><a href=\"https:\/\/oncubanews.com\/en\/cuba\/science-cuba\/science-in-cuba\/massive-intervention-with-covid-19-vaccines-will-begin-in-may-in-havana\/\"><span style=\"font-weight: 400;\">the mass intervention that should begin in May<\/span><\/a><span style=\"font-weight: 400;\"> in the capital and in which the authorities intend to immunize 1.7 million people.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Soberana 02, the other most advanced Cuban vaccine candidate, is also currently in phase III of clinical trials in the city of Havana, in which 44,010 volunteers aged between 19 and 80 years are participating, and will also be tested in Iran, where 100,000 doses of the formula have been sent.<\/span><\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"EM8nEO8PAi\"><p><a href=\"https:\/\/oncubanews.com\/en\/coronavirus\/iran-begins-phase-iii-of-clinical-trials-with-cuban-soberana-02-vaccine-candidate\/\">Iran begins phase III of clinical trials with Cuban Soberana 02 vaccine candidate<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Iran begins phase III of clinical trials with Cuban Soberana 02 vaccine candidate&#8221; &#8212; OnCubaNews English\" src=\"https:\/\/oncubanews.com\/en\/coronavirus\/iran-begins-phase-iii-of-clinical-trials-with-cuban-soberana-02-vaccine-candidate\/embed\/#?secret=L58XoyaFVm#?secret=EM8nEO8PAi\" data-secret=\"EM8nEO8PAi\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">None of the Cuban candidates yet has the authorization for emergency use or registration, but the authorities and experts hope to achieve it soon based on the results of these studies, to start the mass vaccination on the island. If so, Cuba would be the first country in Latin America to have its own COVID-19 vaccine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To date, Cuba has registered more than 108,000 positive cases with SARS-CoV-2 and 664 deaths from the disease. Since January, the island has been going through a third wave of infections, with more than a thousand cases a day on average in recent weeks and an increase in mortality, which experts attribute to the greater transmissibility of the new strains circulating in the country and the population\u2019s low-risk perception.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The Cuban government has not purchased vaccines in the international market, nor is it part of the COVAX Mechanism created under the sponsorship of the World Health Organization (WHO) to promote equitable access to immunization in low- and middle-income nations. Instead, it has bet on its renowned biopharmaceutical industry to face the pandemic and achieve this year the immunization of the island\u2019s inhabitants.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">EFE\/OnCuba<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The study applied in three-shot doses included more than 48,000 volunteers from the capitals of Santiago de Cuba, Guant\u00e1namo and Granma provinces, in order to test its effectiveness against COVID-19.<\/p>\n","protected":false},"author":3134,"featured_media":238410,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[33393],"tags":[33526,33386],"ppma_author":[33546],"class_list":["post-238408","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-coronavirus","tag-abdala","tag-cuban-vaccine-against-covid-19"],"acf":[],"yoast_head":"<!-- This site is optimized 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