
{"id":241333,"date":"2021-07-09T14:10:10","date_gmt":"2021-07-09T18:10:10","guid":{"rendered":"https:\/\/oncubanews.com\/en\/?p=241333"},"modified":"2021-07-09T14:10:10","modified_gmt":"2021-07-09T18:10:10","slug":"soberana-02-91-2-effective-in-its-three-dose-scheme","status":"publish","type":"post","link":"https:\/\/oncubanews.com\/en\/cuba\/soberana-02-91-2-effective-in-its-three-dose-scheme\/","title":{"rendered":"Soberana 02: 91.2% effective in its three-dose scheme"},"content":{"rendered":"<p>The general director of the Finlay Vaccine Institute (IFV), Vicente V\u00e9rez Bencomo, announced this Thursday that Soberana 02, in its three-dose scheme with the Soberana Plus booster, achieved an efficacy of 91.2% against symptomatic disease. This figure is higher than that established by the World Health Organization (WHO) to consider SARS-CoV-2 immunogens as effective vaccines.<\/p>\n<p>The result was announced to Cuban President Miguel D\u00edaz-Canel during the meeting of the Temporary Working Group to confront COVID-19. The president congratulated the scientists and said that this shows the determination in their work in such difficult circumstances.<\/p>\n<p>V\u00e9rez Bencomo said that this number is very high and that it is a reflection of 53 weeks of non-stop work.<\/p>\n<p>He further stated that the efficacy of the three-dose scheme was determined in the presence of the Beta variant of SARS-CoV-2, first reported in South Africa, one of the most worrisome ones recognized by the WHO due to its high transmissibility.<\/p>\n<p>\u201cThis is a first step and much remains to be done to contain the transmission of the disease, we cannot rest until all Cubans are vaccinated and will surely not die if they become ill,\u201d he said.<\/p>\n<figure id=\"attachment_241336\" aria-describedby=\"caption-attachment-241336\" style=\"width: 976px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-241336\" src=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1.jpg\" alt=\"\" width=\"976\" height=\"549\" srcset=\"https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1.jpg 976w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1-300x169.jpg 300w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1-768x432.jpg 768w, https:\/\/oncubanews.com\/en\/wp-content\/uploads\/2021\/07\/Vicente-1-750x422.jpg 750w\" sizes=\"auto, (max-width: 976px) 100vw, 976px\" \/><\/a><figcaption id=\"caption-attachment-241336\" class=\"wp-caption-text\">The general director of the Finlay Vaccine Institute, Vicente V\u00e9rez Bencomo. Photo: BBC.<\/figcaption><\/figure>\n<p>On June 19, the IFV reported that in Phase III of clinical trials, the Soberana 02 vaccine candidate, in its two-dose schedule, had demonstrated 62% efficacy, in addition to a confidence interval greater than 40%, also above that required by the WHO (30%).<\/p>\n<p>Soberana 02 is the world\u2019s only conjugated SARS-CoV-2 immunogen. The virus antigen, the receptor-binding domain (RBD), is chemically bound to tetanus toxoid, while Soberana Plus includes two RBDs bound together with aluminum hydroxide and is the only vaccine project that is being studied in the convalescent population.<\/p>\n<p>This last formulation has proven to be a valuable immunity booster, both for people naturally vaccinated with the virus, and for those who received other vaccine candidates, such as Soberana 02.<\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"TvstzRUnbL\"><p><a href=\"https:\/\/oncubanews.com\/cuba\/iran-autoriza-uso-de-emergencia-del-candidato-vacunal-soberana-02\/\">Ir\u00e1n autoriza uso de emergencia del candidato vacunal cubano Soberana 02<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"\u00abIr\u00e1n autoriza uso de emergencia del candidato vacunal cubano Soberana 02\u00bb \u2014 OnCubaNews\" src=\"https:\/\/oncubanews.com\/cuba\/iran-autoriza-uso-de-emergencia-del-candidato-vacunal-soberana-02\/embed\/#?secret=GiitbBAflT#?secret=TvstzRUnbL\" data-secret=\"TvstzRUnbL\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>The IFV specialists have said that it is more advisable to use Soberana Plus, which is less complex but highly immunogenic, as it only includes the protein that the immune system needs to reactivate its memory cells.<\/p>\n<p>Based on these results, the Center for State Control of Medicines, Equipment and Medical Devices will be able to officially register Soberana 02 plus Soberana Plus as a vaccine, issue the emergency use authorization and move towards a future mass vaccination of the Cuban population.<\/p>\n<p>On June 29 Soberana 02 was authorized for emergency use in the Islamic Republic of Iran, granted to the Pasteur Institute of Iran, which will market the vaccine in that country under the name Pasteur as part of a collaboration agreement with the IFV.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This figure is higher than that established by the World Health Organization (WHO) to consider SARS-CoV-2 immunogens as effective vaccines.<\/p>\n","protected":false},"author":3134,"featured_media":241335,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13902],"tags":[29532,15273,33386,33462],"ppma_author":[33546],"class_list":["post-241333","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cuba","tag-coronavirus-in-cuba","tag-cuban-science","tag-cuban-vaccine-against-covid-19","tag-soberana-02"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Soberana 02: 91.2% 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